I think that this is your last one.

我想这是你最后一杯了。

I think you've had enough.

我想你已经喝得差不多了。

That's all for you,bud.

老伙计，喝完就别再喝了。

Haven't you had about enough?

你喝得差不多了吧？

Do you really think you ought have another one?

你真的认为你还应该再来一杯？

He's feeling no pain.

他醉得不省人事了。

He's drunk as a skunk.

他已烂醉如泥。

He's three sheets to the wind.

他已喝醉，神志不清了。

He's stone drunk.

他已完全醉了。

He's tanked.

他已醉熏熏的。

He's pickled./He's as drunk as a lord.

他已酩酊大醉。